Geminal 18F-oxyfluorination of diazoketones was performed in the presence of rhodium mediators. The reactions were performed using a hypervalent iodine-based [18F]fluoro-benziodoxole reagent. By this methodology various α-[18F]fluoro ethers were obtained in high radiochemical yield (up to 98%) and molar activity (216 GBq μmol−1).
M. A. Cortés González, X. Jiang, P. Nordeman, G. Antoni and K. J. Szabó, Chem. Commun., 2019, 55, 13358 DOI: 10.1039/C9CC06905D
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