A recyclable Amberlyst-15-catalyzed three-component reaction in water to synthesize diarylmethyl sulfones†
Abstract
A recyclable Amberlyst-15-catalyzed three-component reaction in water was developed to synthesize asymmetric diarylmethyl sulfones in good to excellent yields with a wide substrate scope. Asymmetric diarylmethyl sulfones were prepared via C–C and C–S bond formation in a single step between easily available aryl/alkyl aldehydes, sodium aryl/alkyl sulfinates and tri/dimethoxybenzenes.