Issue 11, 2019, Issue in Progress
From the journal:

RSC Advances

Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles†

Qin Yang,a   Zhijian Yin,a   Lifang Zheng,a   Jianjun Yuan,a   Song Wei,a   Qiuping Ding ORCID logo *a  and  Yiyuan Peng ORCID logo *a  

* Corresponding authors

a Key Laboratory of Functional Small Organic Molecule, Ministry of Education, Jiangxi Province's Key Laboratory of Green Chemistry, Jiangxi Normal University, Nanchang, Jiangxi, China
E-mail: yypeng@jxnu.edu.cn, dqpjxnu@gmail.com

Abstract

A novel and simple protocol for the synthesis of 4-(indole-3-yl)quinazolines via cross-dehydrogenative coupling of quinazoline-3-oxides and indoles under an air atmosphere has been developed. A series of biheteroaryl products were obtained in moderate to good yields.

Graphical abstract: Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles

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Article information

DOI
https://doi.org/10.1039/C8RA09864F
Article type
Paper
Submitted
30 Nov 2018
Accepted
11 Feb 2019
First published
18 Feb 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 5870-5877

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Copper-catalyzed cross-dehydrogenative coupling between quinazoline-3-oxides and indoles

Q. Yang, Z. Yin, L. Zheng, J. Yuan, S. Wei, Q. Ding and Y. Peng, RSC Adv., 2019, 9, 5870 DOI: 10.1039/C8RA09864F

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