Issue 30, 2019, Issue in Progress

Novel polythiophene derivative for dual-channel cell imaging

Abstract

Fluorescent materials play an extremely important role in understanding the microbiological world. New fluorescent materials which have good photophysical properties, low cytotoxicity, and multi-channel fluorescent imaging capability are still urgently needed, even though many kinds of fluorescent materials have already been synthesized. In this work, a new polythiophene derivative (PT-OH-PPR) modified with a porphyrin group in its side chain was designed and fabricated through FeCl3 oxidative polymerization. The obtained PT-OH-PPR has wide absorption and emission spectral range, good water solubility and low cytotoxicity. Importantly it could be enriched in the cytoplasm of A549 cells and be excited by two excitation wavelengths (488 nm and 559 nm), which provides a promising application in dual-channel cell imaging.

Graphical abstract: Novel polythiophene derivative for dual-channel cell imaging

Article information

Article type
Paper
Submitted
19 Feb 2019
Accepted
23 May 2019
First published
03 Jun 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 17335-17340

Novel polythiophene derivative for dual-channel cell imaging

F. Wang, H. Xia, S. Pu, N. Yan, J. Song, Y. Tian, J. Wei and L. Yan, RSC Adv., 2019, 9, 17335 DOI: 10.1039/C9RA01262A

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