Issue 39, 2019

Efficient production of coenzyme Q10 from acid hydrolysate of sweet sorghum juice by Rhodobacter sphaeroides

Abstract

In order to achieve efficient bioconversion of biomass-derived sugars, acid hydrolysate of sweet sorghum juice (SSJAH) containing abundant fermentable sugars was used for coenzyme Q10 (CoQ10) fermentation by Rhodobacter sphaeroides CQ-09-1. The synthesis of CoQ10 was facilitated when the initial concentration of total sugar was 80.00 g L−1. And the highest CoQ10 titer was obtained when the pH and temperature were maintained at 7.00 and 30.00 °C, respectively. Moreover, corn steep powder (CSP) was proved to be an efficient nitrogen & salt supplement to SSJAH. Under the optimized conditions, the titer of CoQ10 reached 141.95 mg L−1 in a fed-batch fermentation. The CoQ10 titer reported was about two times higher than that obtained in the previous study using wild strains. This process introduces a potential way to produce CoQ10 using the concept of biorefinery, while making full use of sweet sorghum juice (SSJ).

Graphical abstract: Efficient production of coenzyme Q10 from acid hydrolysate of sweet sorghum juice by Rhodobacter sphaeroides

Article information

Article type
Paper
Submitted
26 May 2019
Accepted
12 Jul 2019
First published
18 Jul 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 22336-22342

Efficient production of coenzyme Q10 from acid hydrolysate of sweet sorghum juice by Rhodobacter sphaeroides

Y. Wang, S. Chen, J. Liu, P. Lv, D. Cai and G. Zhao, RSC Adv., 2019, 9, 22336 DOI: 10.1039/C9RA03964C

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