Preparation and characterization of cyanazine–hydroxypropyl-beta-cyclodextrin inclusion complex

Abstract

Due to its poor water solubility, the herbicide cyanazine is usually dissolved in organic reagents when used, which poses a great threat to the environment. Poor water solubility also causes limited herbicidal activity. In our study, the water solubility of cyanazine was increased by forming a cyanazine/hydroxypropyl beta-cyclodextrin (HPβCD) inclusion complex. The formation of the inclusion complex was confirmed by FT-IR, XRD, SEM and other characterization methods. Phase solubility study showed that HPβCD could improve the water solubility of cyanazine. Thermogravimetric analysis indicated that the thermal stability of cyanazine was improved by forming inclusion complex and the biological activity test showed that better herbicidal activity was obtained on the inclusion complex compared with the cyanazine. The results showed that the formation of inclusion complex could improve the application of cyanazine in agricultural production and reduce the risk to the environment.