Issue 51, 2019, Issue in Progress

Cap control: cyclic versus linear oligomerisation in covalent template-directed synthesis

Abstract

Covalent template-directed synthesis was used to oligomerise monomer building blocks in a controlled manner to give exclusively the linear trimer. Competing reaction pathways were blocked by addition of a large excess of a monomeric capping agent. At a concentration of 1 mM, the cap selectively prevented further reaction of the product chain ends to give polymeric and macrocyclic products, but did not interfere with the templating process.

Graphical abstract: Cap control: cyclic versus linear oligomerisation in covalent template-directed synthesis

Supplementary files

Article information

Article type
Paper
Submitted
30 Jul 2019
Accepted
10 Sep 2019
First published
18 Sep 2019
This article is Open Access
Creative Commons BY license

RSC Adv., 2019,9, 29566-29569

Cap control: cyclic versus linear oligomerisation in covalent template-directed synthesis

D. Núñez-Villanueva, M. Ciaccia and C. A. Hunter, RSC Adv., 2019, 9, 29566 DOI: 10.1039/C9RA07233K

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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