Issue 4, 2020
From the journal:

Analyst

Porous antibody-containing protein microparticles as novel carriers for ELISA†

Marina M. Neumann ORCID logo a  and  Dmitry Volodkin ORCID logo *b  

* Corresponding authors

a Fraunhofer Institute for Cell Therapy and Immunology, Am Muehlenberg 13, 14476 Potsdam, Germany

b Nottingham Trent University, School of Science and Technology, Department of Chemistry and Forensics, Clifton Lane, Nottingham NG11 8NS, UK
E-mail: dmitry.volodkin@ntu.ac.uk

Abstract

A new strategy for ELISA-based detection in small volumes based on porous antibody-containing protein microparticles was developed and employed for the determination of human immunoglobulin G demonstrating both increase in sensitivity and decrease in antibody consumption by ten times compared to a conventional planar ELISA.

Graphical abstract: Porous antibody-containing protein microparticles as novel carriers for ELISA

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Article information

DOI
https://doi.org/10.1039/C9AN01888C
Article type
Communication
Submitted
23 Sep 2019
Accepted
17 Oct 2019
First published
20 Dec 2019

Analyst, 2020,145, 1202-1206

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Porous antibody-containing protein microparticles as novel carriers for ELISA

M. M. Neumann and D. Volodkin, Analyst, 2020, 145, 1202 DOI: 10.1039/C9AN01888C

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