Issue 7, 2020

Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins

Abstract

Binding protein scaffolds, such as rcSso7d, have been investigated for use in diagnostic tests; however, the functional performance of rcSso7d has not yet been studied in comparison to antibodies. Here, we assessed the analyte-binding capabilities of rcSso7d and antibodies on cellulose with samples in buffer and 100% human serum.

Graphical abstract: Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins

Supplementary files

Article information

Article type
Communication
Submitted
10 Feb 2020
Accepted
09 Mar 2020
First published
09 Mar 2020
This article is Open Access
Creative Commons BY-NC license

Analyst, 2020,145, 2515-2519

Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins

K. Sung, Y. Jabbour Al Maalouf, Q. R. Johns, E. A. Miller and H. D. Sikes, Analyst, 2020, 145, 2515 DOI: 10.1039/D0AN00299B

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