Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability

Yuezhen He; Xinyue Fan; Jian Sun; Rui Liu; Zhen Fan; Zhijie Zhang; Xin Chang; Baojuan Wang; Feng Gao; Lun Wang

doi:10.1039/C9CC09651E

Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability†

Yuezhen He,

*^a Xinyue Fan,^a Jian Sun,^a Rui Liu,

*^b Zhen Fan,*^b Zhijie Zhang,^b Xin Chang,^c Baojuan Wang,*^c Feng Gao

^a and Lun Wang

^a

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* Corresponding authors

^a Anhui Key Laboratory of Chemo-Biosensing and Ministry of Education Key Laboratory of Functional Molecular Solids, Laboratory of Biosensing and Bioimaging (LOBAB), College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, China
E-mail: hyz2006@ahnu.edu.cn

^b Key Laboratory of Advanced Civil Engineering Materials of Ministry of Education, Department of Polymeric Materials, School of Materials Science and Engineering, Tongji University, Shanghai 201804, China
E-mail: ruiliu@tongji.edu.cn

^c Anhui Provincial Key Laboratory of the Conservation and Exploitation of Biological Resources, College of Life and Science, Anhui Normal University, Wuhu 241000, China
E-mail: wangbaojuan@ahnu.edu.cn

Abstract

Small-sized semiconducting polymer dots (Pdots) provide better tissue and subcellular penetration while minimizing unspecific interactions, and make the fast clearance of Pdots from human bodies possible by urinary excretion. We employ a powerful and scalable technology, flash nanoprecipitation, to prepare Pdots with small sizes (hydrodynamic diameters ∼10 nm).

Chemical Communications

Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability†

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Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability

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