Issue 21, 2020
From the journal:

Chemical Communications

Fluorescence resonance energy transfer (FRET)-based nanoarchitecture for monitoring deubiquitinating enzyme activity†

Yan-Yan Liang,‡a   Jie Zhang,‡bc   Hui Cui,a   Zhen-Shu Shao,b   Chen Cheng,b   Yue-Bo Wang*a  and  Huai-Song Wang ORCID logo *b  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo 255000, China
E-mail: ybwang@sdut.edu.cn

b Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China
E-mail: wanghuaisong@cpu.edu.cn, wanghuai1234@gmail.com

c Tianjin Key Laboratory of Food Biotechnology, Tianjin University of Commerce, Tianjin 300134, China

Abstract

A novel nanoarchitecture (MSN-Tb-UbR) was prepared by modifying rhodamine B-labelled Ubs (Ub-Rs) on the surface of mesoporous silica nanoparticles (MSNs) loaded with Tb3+-complexes. The MSN-Tb-UbR exhibits ratiometric sensing ability for DUB (UCH-L1) with good sensitivity and selectivity.

Graphical abstract: Fluorescence resonance energy transfer (FRET)-based nanoarchitecture for monitoring deubiquitinating enzyme activity

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Article information

DOI
https://doi.org/10.1039/C9CC09808A
Article type
Communication
Submitted
18 Dec 2019
Accepted
06 Feb 2020
First published
06 Feb 2020

Chem. Commun., 2020,56, 3183-3186

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Fluorescence resonance energy transfer (FRET)-based nanoarchitecture for monitoring deubiquitinating enzyme activity

Y. Liang, J. Zhang, H. Cui, Z. Shao, C. Cheng, Y. Wang and H. Wang, Chem. Commun., 2020, 56, 3183 DOI: 10.1039/C9CC09808A

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