We utilized albumin as a reducing agent to establish novel copper-based and pH-sensitive nanocarrier CuNPs with abundant Cu+, which can encapsulate histone deacetylase (HDAC) inhibitor vorinostat to form uniform and stable nanomedicine V-CuNPs for synergistic chromatin remodelling and chemodynamic therapy.
L. Wang, Z. Zhang, Y. Ding, J. Wu, Y. Hu and A. Yuan, Chem. Commun., 2020, 56, 7753 DOI: 10.1039/D0CC00165A
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