Issue 35, 2020
From the journal:

Chemical Communications

A terbium(iii) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(ii) in biological media†

Enrico Falcone, ORCID logo a   Paulina Gonzalez, ORCID logo a   Lucie Lorusso,a   Olivier Sénèque, ORCID logo b   Peter Faller ORCID logo *a  and  Laurent Raibaut ORCID logo *a  

* Corresponding authors

a Institut de Chimie, UMR 7177, CNRS, Université de Strasbourg, 4 Rue Blaise Pascal 67000, Strasbourg, France
E-mail: pfaller@unistra.fr, raibaut@unistra.fr

b Univ. Grenoble Alpes, CNRS, CEA, IRIG, LCBM (UMR 5249), F-38000 Grenoble, France

Abstract

The measurement of exchangeable Cu2+ levels in biological samples is gaining interest in the context of copper-related pathologies. Here, we report a Tb3+ luminescent turn-off sensor for Cu2+ based on the specific and suitable-affinity Xxx-Zzz-His (ATCUN) peptide motif, enabling Cu2+ detection in the presence of a biological fluorescent background.

Graphical abstract: A terbium(iii) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(ii) in biological media

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Article information

DOI
https://doi.org/10.1039/D0CC01007C
Article type
Communication
Submitted
07 Feb 2020
Accepted
23 Mar 2020
First published
26 Mar 2020

Chem. Commun., 2020,56, 4797-4800

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A terbium(III) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(II) in biological media

E. Falcone, P. Gonzalez, L. Lorusso, O. Sénèque, P. Faller and L. Raibaut, Chem. Commun., 2020, 56, 4797 DOI: 10.1039/D0CC01007C

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