A route to virtually unlimited functionalization of water-soluble p-sulfonatocalix[4]arenes†
Alexander
Gorbunov, 
a
Kirill
Puchnin,
a
Valentine
Nenajdenko,
a
Vladimir
Kovalev
a
and
Ivan
Vatsouro
*a
a
Kirill
Puchnin,
a
Valentine
Nenajdenko,
a
Vladimir
Kovalev
a
and
Ivan
Vatsouro
*a
Abstract
The functionality of p-sulfonatocalix[4]arenes can be easily extended using the propargylation/CuAAC reaction sequence, which allows the introduction of up to four substituted triazole units to the narrow rims of the macrocycles while maintaining their cone shapes and water solubility and, thus, biomedical applicability.
![Graphical abstract: A route to virtually unlimited functionalization of water-soluble p-sulfonatocalix[4]arenes](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=D0CC01196G&imageInfo.ImageIdentifier.Year=2020)
Please wait while we load your content...
