Issue 74, 2020

Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes

Abstract

We utilize a facile and gentle strategy to fabricate bacteria mimics (“bacillus” and “coccus”) endowed with carbohydrates, oligodeoxynucleotides and designed shapes via dopamine-polymer based nanoparticle fabrication and DNA-based multivalent interactions. These bacteria mimics with TLR- and CLR-targeted capabilities are demonstrated to exhibit enhanced immune stimulating efficiency.

Graphical abstract: Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes

Supplementary files

Article information

Article type
Communication
Submitted
27 Mar 2020
Accepted
18 May 2020
First published
18 May 2020

Chem. Commun., 2020,56, 10887-10889

Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes

J. Hu, Y. Gu, M. Liu, W. Zhang, H. Chen and G. Chen, Chem. Commun., 2020, 56, 10887 DOI: 10.1039/D0CC02239J

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