We utilize a facile and gentle strategy to fabricate bacteria mimics (“bacillus” and “coccus”) endowed with carbohydrates, oligodeoxynucleotides and designed shapes via dopamine-polymer based nanoparticle fabrication and DNA-based multivalent interactions. These bacteria mimics with TLR- and CLR-targeted capabilities are demonstrated to exhibit enhanced immune stimulating efficiency.
J. Hu, Y. Gu, M. Liu, W. Zhang, H. Chen and G. Chen, Chem. Commun., 2020, 56, 10887 DOI: 10.1039/D0CC02239J
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