Zhenbo Guo, Mei Wang, Xueyan Li, Xu Jia, Xiaoli Wang, Pingzhu Zhang, Chao Wei and Xiaoliu Li
Chem. Commun., 2020,56, 14183-14186
DOI:
10.1039/D0CC05330A,
Communication
A hepatocyte-targeting fluorescent N2H4 probe, GHP, was first designed and synthesized employing N-acetylgalactosamine (GalNAc) as the hepatocyte-targeting group and 3-nitrophthalimide as the recognition moiety. The probe can be used to selectively image N2H4 produced by the hydrolysis of isoniazid in HepG2 cells and the liver of zebrafish in situ.
