Issue 4, 2020
From the journal:

Nanoscale

Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles†

Winda Tasia,ab   Chang Lei, ORCID logo c   Yuxue Cao,ac   Qingsong Ye,a   Yan He*ad  and  Chun Xu ORCID logo *a  

* Corresponding authors

a School of Dentistry, The University of Queensland, Brisbane, Queensland, Australia
E-mail: helen-1101@hotmail.com, chun.xu@uq.edu.au

b School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Australia

c Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, Australia

d Laboratory for Regenerative Medicine, Tianyou Hospital, Wuhan University of Science and Technology, Wuhan, China

Abstract

Deoxyribonuclease I (DNase I) was successfully loaded and delivered by silver-doped mesoporous silica nanoparticles (MSN-Ag) for biofilm treatments. This nanoformulation showed enhanced antibacterial effects for both Gram-negative and Gram-positive biofilms by promoting the biofilm biomass dispersing ability of DNase I.

Graphical abstract: Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C9NR08467C
Article type
Communication
Submitted
02 Oct 2019
Accepted
16 Nov 2019
First published
19 Nov 2019

Nanoscale, 2020,12, 2328-2332

Permissions

Request permissions

Enhanced eradication of bacterial biofilms with DNase I-loaded silver-doped mesoporous silica nanoparticles

W. Tasia, C. Lei, Y. Cao, Q. Ye, Y. He and C. Xu, Nanoscale, 2020, 12, 2328 DOI: 10.1039/C9NR08467C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements