Issue 14, 2020

Silver-catalyzed direct C–H oxidative carbamoylation of quinolines with oxamic acids

Abstract

A silver-catalyzed efficient and direct C–H carbamoylation of quinolines with oxamic acids to access carbamoylated quinolines has been developed through oxidative decarboxylation reaction. The reaction proceeds smoothly over a broad range of substrates with excellent functional group tolerance and excellent yields under mild conditions.

Graphical abstract: Silver-catalyzed direct C–H oxidative carbamoylation of quinolines with oxamic acids

Supplementary files

Article information

Article type
Paper
Submitted
18 Feb 2020
Accepted
21 Mar 2020
First published
23 Mar 2020

Org. Biomol. Chem., 2020,18, 2747-2757

Silver-catalyzed direct C–H oxidative carbamoylation of quinolines with oxamic acids

J. Yuan, Q. Chen, C. Li, J. Zhu, L. Yang, S. Zhang, P. Mao, Y. Xiao and L. Qu, Org. Biomol. Chem., 2020, 18, 2747 DOI: 10.1039/D0OB00358A

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