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A palladium(II)-catalyzed cyclization of 2-ethynylaniline tethered cinnamyl acetate involving aminopalladation/alkene insertion/β-acetoxy elimination cascade processes was established. The new protocol provides efficient access to indenoindoles in moderate to good yields under mild conditions.

Graphical abstract: Palladium(ii)-catalyzed tandem cyclization of 2-ethynylaniline tethered cinnamyl acetate for the synthesis of indenoindoles

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