Ligand-controlled copper-catalyzed 1,2 or 1,4-protoborylation of 2-trifluoromethyl-1,3-conjugated enynes

Abstract

A novel ligand-controlled highly regioselective synthesis of CF₃-substituted homopropargylboronates and homoallenylboronates via copper-catalyzed 1,2 or 1,4-protoborylation of 2-trifluoromethyl-1,3-conjugated enynes with B₂pin₂ was developed.