Issue 18, 2021

Purine-based Ir(iii) complexes for sensing viscosity of endo-plasmic reticulum with fluorescence lifetime imaging microscopy

Abstract

Novel purine-based iridium complexes were designed for selective determination of ER viscosity. The Ir-PH possessed excellent ER targeting ability and could distinguish the viscosity changes under ER stress by fluorescence lifetime image microscopy (FLIM), which may accelerate the development of relative quantitative detection of microenvironment changes at the subcellular level.

Graphical abstract: Purine-based Ir(iii) complexes for sensing viscosity of endo-plasmic reticulum with fluorescence lifetime imaging microscopy

Supplementary files

Article information

Article type
Communication
Submitted
03 Dec 2020
Accepted
22 Jan 2021
First published
25 Jan 2021

Chem. Commun., 2021,57, 2265-2268

Purine-based Ir(III) complexes for sensing viscosity of endo-plasmic reticulum with fluorescence lifetime imaging microscopy

X. Liu, K. Li, L. Shi, H. Zhang, Y. Liu, H. Wang, N. Wang and X. Yu, Chem. Commun., 2021, 57, 2265 DOI: 10.1039/D0CC07867K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements