Nonblinking carbon dots for imaging and tracking receptors on a live cell membrane

Qian Wang; Zhenzhen Feng; Hua He; Xiang Hu; Jian Mao; Xiaoliang Chen; Lihua Liu; Xiaoyun Wei; Di Liu; Simin Bi; Xiaojuan Wang; Baosheng Ge; Daoyong Yu; Fang Huang

doi:10.1039/D1CC01120K

Nonblinking carbon dots for imaging and tracking receptors on a live cell membrane†

Qian Wang,

^a Zhenzhen Feng,^b Hua He,

*^a Xiang Hu,^a Jian Mao,^a Xiaoliang Chen,^a Lihua Liu,^a Xiaoyun Wei,^a Di Liu,^a Simin Bi,^a Xiaojuan Wang,

^a Baosheng Ge,

^a Daoyong Yu^a and Fang Huang

*^a

Author affiliations

* Corresponding authors

^a State Key Laboratory of Heavy Oil Processing and Centre for Bioengineering and Biotechnology, China University of Petroleum (East China), Qingdao, China
E-mail: huahe@upc.edu.cn, fhuang@upc.edu.cn

^b Technical Centre of Qingdao Customs, 99 Huanghe East Road, Huangdao, China

Abstract

Blinking occurs with nearly all fluorophores including organic dyes, fluorescent proteins, semiconductor quantum dots and carbon dots (CDs). We developed non-blinking and photoresistant fluorescent CDs by introducing multiple aromatic domains onto a single carbon dot and demonstrated their great potential for imaging and tracking of receptors on a live cell membrane.

Chemical Communications

Nonblinking carbon dots for imaging and tracking receptors on a live cell membrane†

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Nonblinking carbon dots for imaging and tracking receptors on a live cell membrane

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