Issue 54, 2021
From the journal:

Chemical Communications

A “double-locked” probe for the detection of hydrogen sulfide in a viscous system†

Fanpeng Kong,‡*a   Xiaoxiu Wang,‡a   Jundong Bai,a   Xiao Li,a   Chao Yang,a   Ying Li,a   Kehau Xu ORCID logo *a  and  Bo Tang ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institutes of Biomedical Sciences, Shandong Normal University, Jinan 250014, People's Republic of China
E-mail: kong-fanpeng@163.com, xukehua@sdnu.edu.cn, tangb@sdnu.edu.cn

Abstract

A novel “double-locked” probe, DCO-H2S-V, was prepared for detecting hydrogen sulfide in a highly viscous system. Experiments demonstrated that only when H2S and a high viscosity environment coexist in a cell, can the probe be activated effectively and emit fluorescence. This has been successfully used for detecting the changes in viscosity and H2S in a Parkinson's disease model, PC-12 cells treated with glutamate.

Graphical abstract: A “double-locked” probe for the detection of hydrogen sulfide in a viscous system

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Article information

DOI
https://doi.org/10.1039/D1CC01819A
Article type
Communication
Submitted
06 Apr 2021
Accepted
02 Jun 2021
First published
03 Jun 2021

Chem. Commun., 2021,57, 6604-6607

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A “double-locked” probe for the detection of hydrogen sulfide in a viscous system

F. Kong, X. Wang, J. Bai, X. Li, C. Yang, Y. Li, K. Xu and B. Tang, Chem. Commun., 2021, 57, 6604 DOI: 10.1039/D1CC01819A

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