Issue 67, 2021
From the journal:

Chemical Communications

A light-activatable photosensitizer for photodynamic therapy based on a diarylethene derivative†

Jian Zhang,‡a   Ran Zhang,‡a   Kaiqiang Liu,a   Yong Li,a   Xu Wang,*a   Xilei Xie,a   Xiaoyun Jiaoa  and  Bo Tang ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn, wangxu@sdnu.edu.cn

Abstract

Herein, a light-activatable photosensitizer based on a diarylethene derivative, DAE-TPE, was developed for photodynamic therapy. Upon UV exposure, the “opened” form (OF) of DAE-TPE NPs was converted to the “closed” form (CF), and photosensitization was activated. The CF of DAE-TPE NPs exhibited sufficient photodynamic therapy effects upon HeLa cells.

Graphical abstract: A light-activatable photosensitizer for photodynamic therapy based on a diarylethene derivative

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Article information

DOI
https://doi.org/10.1039/D1CC02102H
Article type
Communication
Submitted
20 Apr 2021
Accepted
12 Jul 2021
First published
15 Jul 2021

Chem. Commun., 2021,57, 8320-8323

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A light-activatable photosensitizer for photodynamic therapy based on a diarylethene derivative

J. Zhang, R. Zhang, K. Liu, Y. Li, X. Wang, X. Xie, X. Jiao and B. Tang, Chem. Commun., 2021, 57, 8320 DOI: 10.1039/D1CC02102H

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