Issue 80, 2021
From the journal:

Chemical Communications

Transcription–translation of the Escherichia coli genome within artificial cells†

Tatsuki Deyama,a   Yukino Matsui, ORCID logo a   Yuhei Chadani, ORCID logo b   Yasuhiko Sekine,c   Nobuhide Doia  and  Kei Fujiwara ORCID logo *a  

* Corresponding authors

a Department of Biosciences & Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223–8522, Japan
E-mail: fujiwara@bio.keio.ac.jp

b Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, S2-19, 4259 Nagatsuta, Midori-ku, Yokohama 226-8503, Japan

c Department of Life Science, College of Science, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan

Abstract

Here we created artificial cells in which information of the genome of living cells is expressed by the elements encoded in the genome. We confirmed that the system works normally within artificial cells, which paves the way for reconstructing living cells from biomolecules.

Graphical abstract: Transcription–translation of the Escherichia coli genome within artificial cells

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Article information

DOI
https://doi.org/10.1039/D1CC04401J
Article type
Communication
Submitted
11 Aug 2021
Accepted
11 Sep 2021
First published
13 Sep 2021

Chem. Commun., 2021,57, 10367-10370

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Transcription–translation of the Escherichia coli genome within artificial cells

T. Deyama, Y. Matsui, Y. Chadani, Y. Sekine, N. Doi and K. Fujiwara, Chem. Commun., 2021, 57, 10367 DOI: 10.1039/D1CC04401J

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