The copper-catalyzed selective monoalkylation of active methylene compounds with alkylsilyl peroxides†
Yan
Liu 
*a
and
Keiji
Maruoka
*ab
*a
and
Keiji
Maruoka
*ab
Abstract
A novel method for a mild copper-catalyzed selective monoalkylation of active methylene compounds with various alkylsilyl peroxides has been developed. The reaction has a broad substrate scope and our mechanistic studies suggest the participation of radical species in this alkylation reaction.
- This article is part of the themed collection: Synthetic methodology in OBC
Please wait while we load your content...
