Synthesis of selenated tetracyclic indoloazulenes via iodine and diorganyl diselenides†
Abstract
Herein, we report an efficient protocol for the synthesis of selenated tetracyclic indoloazulenes. The reaction of diorganyl diselenides with molecular iodine in dichloromethane leads to the in situ formation of organo selenenyl iodide. The synthesis of selenylated tetracyclic indoloazulenes through intramolecular cascade cyclization has been achieved via organo selenenyl iodide and bisindole at room temperature under metal-free conditions in good yields. All compounds were fully characterized by the FT-IR, HRMS, and 1H, 13C and 77Se NMR spectral data.
- This article is part of the themed collection: Synthetic methodology in OBC