Issue 14, 2021

Synthesis of selenated tetracyclic indoloazulenes via iodine and diorganyl diselenides

Abstract

Herein, we report an efficient protocol for the synthesis of selenated tetracyclic indoloazulenes. The reaction of diorganyl diselenides with molecular iodine in dichloromethane leads to the in situ formation of organo selenenyl iodide. The synthesis of selenylated tetracyclic indoloazulenes through intramolecular cascade cyclization has been achieved via organo selenenyl iodide and bisindole at room temperature under metal-free conditions in good yields. All compounds were fully characterized by the FT-IR, HRMS, and 1H, 13C and 77Se NMR spectral data.

Graphical abstract: Synthesis of selenated tetracyclic indoloazulenes via iodine and diorganyl diselenides

Supplementary files

Article information

Article type
Paper
Submitted
12 Feb 2021
Accepted
14 Mar 2021
First published
15 Mar 2021

Org. Biomol. Chem., 2021,19, 3199-3206

Synthesis of selenated tetracyclic indoloazulenes via iodine and diorganyl diselenides

K. M. N. Win, A. D. Sonawane and M. Koketsu, Org. Biomol. Chem., 2021, 19, 3199 DOI: 10.1039/D1OB00268F

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