Issue 37, 2021

Synthesis and sequencing of informational poly(amino phosphodiester)s

Abstract

Sequence-defined poly(amino phosphodiester)s containing main-chain tertiary amines were synthesized by automated solid-phase phosphoramidite chemistry. These polymers were prepared using four monomers with different substituents. The formed polymers were characterized by HPLC and mass spectrometry. These methods evidenced preparation of molecularly-defined polymers. Furthermore, the presence of tertiary amines in the polymer backbones facilitates sequencing by tandem mass spectrometry.

Graphical abstract: Synthesis and sequencing of informational poly(amino phosphodiester)s

Supplementary files

Article information

Article type
Communication
Submitted
06 Aug 2021
Accepted
10 Sep 2021
First published
13 Sep 2021

Polym. Chem., 2021,12, 5279-5282

Synthesis and sequencing of informational poly(amino phosphodiester)s

I. Roszak, L. Oswald, A. Al Ouahabi, A. Bertin, E. Laurent, O. Felix, I. Carvin-Sergent, L. Charles and J. Lutz, Polym. Chem., 2021, 12, 5279 DOI: 10.1039/D1PY01052B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements