Issue 79, 2022
From the journal:

Chemical Communications

Damage-free evaluation of cultured cells based on multivariate analysis with a single-polymer probe†

Hiroka Sugai, ORCID logo *ab   Shunsuke Tomita, ORCID logo b   Sayaka Ishihara,b   Kentaro Shirakia  and  Ryoji Kurita ORCID logo *ab  

* Corresponding authors

a Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan
E-mail: sugai.hiroka.fn@u.tsukuba.ac.jp

b Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Higashi, Tsukuba, Ibaraki, Japan
E-mail: r.kurita@aist.go.jp

Abstract

We present a pattern-recognition-based sensor that targets cell-derived components in culture media and evaluates cultured cells without damaging them. An array sensor made of a single-polymer probe was employed to obtain fluorescence response patterns of the analyte media, allowing successful identification of the type and state of the cells via multivariate analysis.

Graphical abstract: Damage-free evaluation of cultured cells based on multivariate analysis with a single-polymer probe

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Article information

DOI
https://doi.org/10.1039/D2CC03308A
Article type
Communication
Submitted
12 Jun 2022
Accepted
12 Sep 2022
First published
12 Sep 2022

Chem. Commun., 2022,58, 11083-11086

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Damage-free evaluation of cultured cells based on multivariate analysis with a single-polymer probe

H. Sugai, S. Tomita, S. Ishihara, K. Shiraki and R. Kurita, Chem. Commun., 2022, 58, 11083 DOI: 10.1039/D2CC03308A

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