Issue 67, 2022
From the journal:

Chemical Communications

Temporal control of protein labeling by a photo-caged benzaldehyde motif and discovery of host cell factors of avian influenza virus infection†

Nicholas Asiimwe, ORCID logo ‡a   Jung Hoon Lee,‡b   Kyung Tae Hong,‡a   Dhiraj P. Murale,‡c   Md. Mamunul Haque, ORCID logo b   Dong-Hoon Kimb  and  Jun-Seok Lee ORCID logo *b  

* Corresponding authors

a Bio-Med Program KIST-School UST, Korea University College of Medicine, Seoul, Republic of Korea

b Department of Pharmacology, Korea University College of Medicine, Seoul 02792, Republic of Korea
E-mail: junseoklee@korea.ac.kr

c Center for Advanced Biomolecular Recognition, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea

Abstract

Photo-caged benzaldehyde probes using o-nitrophenylethylene glycol were designed for photo-activated electrophile generation. Using photo-activated electrophile generating probes, we successfully revealed under-represented host cell response factors using an avian influenza virus infection model.

Graphical abstract: Temporal control of protein labeling by a photo-caged benzaldehyde motif and discovery of host cell factors of avian influenza virus infection

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Article information

DOI
https://doi.org/10.1039/D2CC04091C
Article type
Communication
Submitted
22 Jul 2022
Accepted
22 Jul 2022
First published
27 Jul 2022

Chem. Commun., 2022,58, 9345-9348

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Temporal control of protein labeling by a photo-caged benzaldehyde motif and discovery of host cell factors of avian influenza virus infection

N. Asiimwe, J. H. Lee, K. T. Hong, D. P. Murale, Md. M. Haque, D. Kim and J. Lee, Chem. Commun., 2022, 58, 9345 DOI: 10.1039/D2CC04091C

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