Retracted Article: Enantioselective synthesis of α-tetrasubstituted (3-indolizinyl) (diaryl)methanamines via chiral phosphoric acid catalysis

Jialing Zhong; Rihuang Pan; Xufeng Lin

doi:10.1039/D2RA03750E

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Retracted Article: Enantioselective synthesis of α-tetrasubstituted (3-indolizinyl) (diaryl)methanamines via chiral phosphoric acid catalysis†

Jialing Zhong,^a Rihuang Pan^a and Xufeng Lin

*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. China
E-mail: lxfok@zju.edu.cn

Abstract

An enantioselective Friedel–Crafts reaction of cyclic α-diaryl N-acyl imines with indolizines catalyzed by a chiral spirocyclic phosphoric acid has been developed. The asymmetric transformation proceeds smoothly to afford α-tetrasubstituted (3-indolizinyl) (diaryl)methanamines in good yields with up to 98% ee under mild conditions.