A compact, practical photoreactor for multi-reaction arrays

Abstract

The Bristol Myers Squibb Photoreactor (BMS-PR) is a convenient, small-footprint platform that enables routine use of photochemical transformations in a variety of laboratory settings. These photoreactors have been engineered to safely irradiate multiple reaction vessels for array synthesis at various wavelengths and temperatures with a more practical setup than most other commercial photoreactors. The BMS-PR integrates seamlessly with standard laboratory equipment and incorporates a variety of attractive safety features. Herein we describe the BMS-PR460 device for irradiation of reactions at 460 nm using blue light-emitting diodes (LEDs) and highlight its application with photochemical reactions that may be useful in the discovery of novel drug molecules.