Tf2O/DMSO-mediated dual activation of aryl phosphinate to access various aryl phosphonates†
Shang-Dong
Yang 
b
and
Bin
Yang
*a
b
and
Bin
Yang
*a
Abstract
A metal-free method for the dual activation of aryl phosphinate has been developed; the P–H and P–O bonds are sequentially activated by the Tf2O/DMSO system. Without the requirement of metals and unstable P-reagents, this one-pot procedure provides a convenient and practical access to a variety of aryl phosphonates. A mechanism involving twice generation of electrophilic P-species and two SN-processes is proposed on the basis of the control experiments.
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