Simultaneously recorded photochemical action plots reveal orthogonal reactivity

Abstract

We map the photochemical reactivity of two chromophores—a pyrene-chalcone and a methylene blue protected amine—from a one-pot reaction mixture based on their dynamic absorptivity changes upon light exposure, constructing a dual action plot. We employ the action plot data to determine a pathlength-independent λ-orthogonality window, allowing the orthogonal folding of distinct polymer chains into single chain nano-particles (SCNPs) from the same reaction mixture.