Design of target response wettability switchable core–shell–shell electrochemiluminescence nanoprobes for sensitive hyaluronidase detection

Abstract

Electrochemiluminescence nanoprobes with a core–shell–shell structure have been designed and applied for hyaluronidase detection. The nanoprobes can precipitate efficiently through target-regulation wettability for collection, and enrich near to the hydrophobic electrode surface through hydrophobic interaction to enhance the performance of the biosensor.