PhI(OAc)2/Pd(OAc)2 promoted the formation of 8-hydroxyquinoline derivatives from benzoxazoles and alcohols

Qingkun Wu; Jingxuan Hou; Qingshan Gu; Hui Gao; Meiqi Shi; Lu Zheng

doi:10.1039/D2OB01712A

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PhI(OAc)₂/Pd(OAc)₂ promoted the formation of 8-hydroxyquinoline derivatives from benzoxazoles and alcohols†

Qingkun Wu,^a Jingxuan Hou,^a Qingshan Gu,^a Hui Gao,^a Meiqi Shi^a and Lu Zheng

*^a

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* Corresponding authors

^a School of Pharmacy, Jiangsu Ocean University, Lianyungang, China
E-mail: zhel-123@163.com

Abstract

A PhI(OAc)₂/Pd(OAc)₂ system that synergistically promotes the formation of 8-hydroxyquinoline derivatives from benzoxazoles and alcohols has been developed. The reaction proceeded smoothly with a range of benzoxazoles and alcohols to give the corresponding 8-hydroxyquinoline derivatives in moderate yields.

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Article information

DOI: https://doi.org/10.1039/D2OB01712A
Article type: Communication
Submitted: 20 Sep 2022
Accepted: 04 Jan 2023
First published: 04 Jan 2023

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Org. Biomol. Chem., 2023,21, 1148-1152

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PhI(OAc)₂/Pd(OAc)₂ promoted the formation of 8-hydroxyquinoline derivatives from benzoxazoles and alcohols

Q. Wu, J. Hou, Q. Gu, H. Gao, M. Shi and L. Zheng, Org. Biomol. Chem., 2023, 21, 1148 DOI: 10.1039/D2OB01712A

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Organic & Biomolecular Chemistry