C10H10ClNO3: exploration of birefringent crystals in an isoquinoline system

Abstract

A new crystal, C₁₀H₁₀ClNO₃, was prepared by the solution evaporation technique. It shows a large birefringence of 0.345@550 nm and high thermal stability. Structural analysis and theoretical calculations demonstrate that the isoquinoline carboxylic acid is responsible for optical anisotropy and can be used as an excellent birefringence-active gene.