A field guide to flow chemistry for synthetic organic chemists†
Abstract
Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious “black box” needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By “lifting the veil” on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.
- This article is part of the themed collections: Most popular 2023 organic chemistry articles, 2023 Chemical Science Perspective & Review Collection, 2023 Chemical Science HOT Article Collection and 2023 ChemSci Pick of the Week Collection