Volume 2, 2023

Design and development of a fluorometric and colorimetric sensor for toxic cyanide detection by pyridinium scaffolds: live cell imaging and real sample analysis

Abstract

Polyheteroaryl pyridinium-based indenophenanthridine is synthesized using the conventional method. The synthesized pyridinium core indenophenanthridine detects cyanide ion (CN) in a ratiometric manner with an excellent detection limit (1.2 nM). The CN sensing ability of the probe was treated for practical applications in food extracts, water samples, and U87 cell lines. The probe successfully detected the CN anion in real samples and cell lines.

Graphical abstract: Design and development of a fluorometric and colorimetric sensor for toxic cyanide detection by pyridinium scaffolds: live cell imaging and real sample analysis

Supplementary files

Article information

Article type
Paper
Submitted
12 Sep 2022
Accepted
18 Nov 2022
First published
23 Nov 2022
This article is Open Access
Creative Commons BY license

Sens. Diagn., 2023,2, 337-346

Design and development of a fluorometric and colorimetric sensor for toxic cyanide detection by pyridinium scaffolds: live cell imaging and real sample analysis

K. Jamuna, S. Gayathri, S. Sivakumar and B. Ashokkumar, Sens. Diagn., 2023, 2, 337 DOI: 10.1039/D2SD00163B

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