First electrochemical bioplatforms to determine anti-centromere B antibodies: critical comparison between integrated and magnetic bead-assisted strategies using His-tag chemistry†
Abstract
This work reports and compares the first electrochemical bioplatforms for determining anti-centromere B antibodies developed in magnetic microbead-assisted or integrated formats and proves the competitiveness of the nitrilotriacetic acid chemistry they exploit against common carbodiimide/succinimide-based one and their potential to determine serum target autoantibodies at clinically relevant levels.
- This article is part of the themed collection: Sensors & Diagnostics — Editors Choice Collection 2023