A sensitive electrochemical sensor based on CoWO4/multi-walled carbon nanotubes for the selective determination of chlorpromazine hydrochloride

Abstract

In this work, a novel electrochemical sensor based on cobalt tungstate/multi-walled carbon nanotubes (CoWO4/MWCNTs) nanocomposite has been used to detect chlorpromazine hydrochloride (CPZ). The CoWO4/MWCNTs nanocomposite was obtained by solvothermal technology and ultrasonic method and analyzed via different characterization techniques of scanning electron microscope (SEM), X-ray diffractometer (XRD), energy dispersive spectroscopy (EDS) and X-ray photoelectron spectroscopy (XPS). The electrochemical behavior of CoWO4/MWCNTs/GCE was explored using cyclic voltammetry (CV). Electrochemical experiments have confirmed that CoWO4/MWCNTs/GCE exhibits excellent electrocatalytic activity towards CPZ with good selectivity, reproducibility and stability. The linear dynamic range of CPZ was observed to be 1-2000 µM with a detection limit of 0.33 µM. Moreover, the actual sample was analyzed using lake water with satisfactory results, which endows the sensor as potential candidates for the detection of CPZ.