Issue 16, 2024

White-light-emitting diode (LED)-promoted one-pot synthesis of 1,2-dihydropyrimido[1,2-a]benzimidazoles in the presence of a new spiky magnetic nanocatalyst and their anthelmintic studies

Abstract

Spiky Ni-nanoparticles were successfully synthesized and characterized using different analytical techniques, including Fourier transform infrared spectroscopy (FT-IR), field electron scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), powder XRD, vibrating-sample magnetometry (VSM), and energy-dispersive X-ray spectroscopy (EDS). These nanoparticles, which exhibited a large surface area and magnetic properties, were meticulously used for the synthesis of 1,2-dihydropyrimido[1,2-a]benzimidazole and its derivatives from an aromatic aldehyde, active methylene compounds, and 2-aminobenzimidazole at room temperature under white LED irradiation. This method capitalizes on mild and environmentally friendly reaction conditions, high selectivity, and excellent yield of products, as well as the recyclability and reusability of the catalyst. In addition, the prepared benzimidazole derivatives 6d, 6k, and 8e exhibited positive anthelmintic activity against S. obvelata, a model gastrointestinal nematode.

Graphical abstract: White-light-emitting diode (LED)-promoted one-pot synthesis of 1,2-dihydropyrimido[1,2-a]benzimidazoles in the presence of a new spiky magnetic nanocatalyst and their anthelmintic studies

Supplementary files

Article information

Article type
Paper
Submitted
07 Jun 2024
Accepted
29 Jun 2024
First published
01 Jul 2024

Catal. Sci. Technol., 2024,14, 4608-4621

White-light-emitting diode (LED)-promoted one-pot synthesis of 1,2-dihydropyrimido[1,2-a]benzimidazoles in the presence of a new spiky magnetic nanocatalyst and their anthelmintic studies

G. K. Kharmawlong, B. Chettri, R. Rymbai, R. Nongrum, A. K. Yadav, S. Bhan and R. Nongkhlaw, Catal. Sci. Technol., 2024, 14, 4608 DOI: 10.1039/D4CY00723A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements