A biomimetic approach to lycogarubin C, lynamicin D and related analogues

Abstract

An efficient and biomimetic synthetic approach to 3,4-diindolylpyrrole-2,5-dicarboxylate derivatives, including lycogarubin C, lynamicin D and related analogues, was discovered. The crucial transformation included the one-pot formation of two C–N bonds and one C–C bond to construct characteristic pyrrole rings.