Issue 30, 2024

An AIE-active tetra-aryl imidazole-derived chemodosimeter for turn-on recognition of hydrazine and its bioimaging in living cells

Abstract

A new chemodosimeter SWJT-31 with an aggregation-induced emission (AIE) effect was designed and constructed. Upon increasing the water fraction in the solution, it exhibited typical AIE, which showed bright red fluorescence at 610 nm. SWJT-31 could sensitively and specifically recognize hydrazine by the TICT effect with an LOD of 33.8 nM, which was much lower than the standard of the USEPA. A portable test strip prepared using SWJT-31 was also developed for the visual detection of hydrazine. Eventually, it was successfully used for the detection of hydrazine in water samples and HeLa cells.

Graphical abstract: An AIE-active tetra-aryl imidazole-derived chemodosimeter for turn-on recognition of hydrazine and its bioimaging in living cells

Supplementary files

Article information

Article type
Paper
Submitted
16 Jun 2024
Accepted
09 Jul 2024
First published
16 Jul 2024

Org. Biomol. Chem., 2024,22, 6135-6140

An AIE-active tetra-aryl imidazole-derived chemodosimeter for turn-on recognition of hydrazine and its bioimaging in living cells

Q. Li, Y. Yuan, R. Cheng, Y. Ma, R. Tan, Y. Wang and Y. Peng, Org. Biomol. Chem., 2024, 22, 6135 DOI: 10.1039/D4OB01009D

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