Electrochemical (radio)-halodesilylation of aromatic silanes

Abstract

We have developed a green and efficient electrochemical halodesilylation of trimethylsilanes to synthesize aryl halides. The reaction was carried out under mild conditions without sophisticated equipment, transition metal catalysts, hazardous oxidants, and additional electrolytes. The protocol also has broad substrate scope and high functional group tolerance. Moreover, this electrochemical method is applicable to radioactive iodine labeling.