Solvent dependent hierarchical dual helicity in a fused [4]carbohelicene/quinoline oligoamide foldamer

Abstract

Two classes of helical motif, namely a [4]carbohelicene and an aromatic oligoamide foldamer, were fused to form a hybrid molecular construct in which their helical axes are parallel. Depending on the solvent, the [4]carbohelicene can bias the dynamic screw sense of the aromatic oligoamide with a reverse handedness.