Issue 10, 2025

A novel small-molecule fluorescent probe caused by minimal structural modifications for specific staining of the cell nuclear membrane

Abstract

The nuclear membrane is a double-layered structure that physically protects the cell's DNA from the chemical reactions occurring in other parts of the cell. In this study, we present the first brand-new small-molecule fluorescent probe that selectively stains the nuclear membrane, allowing for the visualization of nuclear morphology without interfering with the DNA's activity.

Graphical abstract: A novel small-molecule fluorescent probe caused by minimal structural modifications for specific staining of the cell nuclear membrane

Supplementary files

Article information

Article type
Communication
Submitted
22 Dec 2024
Accepted
01 Jan 2025
First published
13 Jan 2025

Chem. Commun., 2025,61, 2107-2110

A novel small-molecule fluorescent probe caused by minimal structural modifications for specific staining of the cell nuclear membrane

W. Jin, Y. Liu, Q. Lu, J. Huang, Z. Liu and X. Yu, Chem. Commun., 2025, 61, 2107 DOI: 10.1039/D4CC06678B

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