An intelligent INH@ZIF@MnO2/HA nanotherapeutic platform, ingeniously engineered to augment tumor-specific oxidative stress in chemodynamic therapy, effectively harnesses the isoniazid (INH)-mediated generation of highly reactive non-Fenton-type hydroxyl radicals (•OH) catalyzed by Mn2+ ions.
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Y. Miao, J. An, X. Liang, B. Su, T. Chen, J. Wang, Y. Cai, S. Zhu, Y. Yao and Y. Wang, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D5CC03099D
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