Microscopic Menace: Exploring the Link Between Microplastics and Cancer Pathogenesis

Abstract

Microplastics represent a group of emerging environmental contaminants widely recognized for their potential impacts on human health, particularly concerning the pathogenesis of cancer. This review aims to engage with the intricate dimensions of microplastics, classification and persistence across different ecosystems. It underscores their bioaccumulation and pervasive presence. Although significant insights have been garnered, much remains to be elucidated regarding the full spectrum of impact microplastics have on human health. Evidence derived from both epidemiological and experimental studies underscores the urgent necessity for clinical research to elucidate the microplastic-cancer connection. It is a very important concern in biomedicine as cancer remains the leading cause of mortality irrespective of the advancement in diagnostic and therapeutic regimens. Furthermore, improvements in the detection and analysis of microplastics within biological samples are also scrutinized. The article concludes with future directions which advocate for standardized research protocols, regulatory measures and interdisciplinary collaboration to confront the microscopic threat posed by microplastics in cancer pathogenesis. However, this endeavour necessitates concerted efforts across various scientific domains, because only through such collaboration can we hope to achieve meaningful progress in understanding this critical issue.

Supplementary files

Transparent peer review

To support increased transparency, we offer authors the option to publish the peer review history alongside their article.

View this article’s peer review history

Article information

Article type
Critical Review
Submitted
26 Mar 2025
Accepted
15 May 2025
First published
22 May 2025
This article is Open Access
Creative Commons BY license

Environ. Sci.: Processes Impacts, 2025, Accepted Manuscript

Microscopic Menace: Exploring the Link Between Microplastics and Cancer Pathogenesis

M. M. Joseph, J. B. Nair and A. M. Joseph, Environ. Sci.: Processes Impacts, 2025, Accepted Manuscript , DOI: 10.1039/D5EM00232J

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements